CALBIOCHEM -- ETHIDIUM BROMIDE, 331565 -- 6505-00N092485 
=====================  Product Identification  =====================

Product ID:ETHIDIUM BROMIDE, 331565
MSDS Date:03/02/1999
FSC:6505
NIIN:00N092485
Status Code:A
=== Responsible Party ===
Company Name:CALBIOCHEM
Box:12087
City:LA JOLLA
State:CA
ZIP:92039-2087
Country:US
Info Phone Num:800-854-3417
Emergency Phone Num:800-424-9300 (CHEMTREC)
Resp. Party Other MSDS Num.:331565
Chemtrec Ind/Phone:(800)424-9300
CAGE:29089
=== Contractor Identification ===
Company Name:CALBIOCHEM
Box:12087
City:LA JOLLA
State:CA
ZIP:92039-2087
Country:US
Phone:619-450-5558; 800-854-3417
CAGE:29089

=============  Composition/Information on Ingredients  =============

Ingred Name:ETHIDIUM BROMIDE
CAS:1239-45-8
RTECS #:SF7950000
Code:F
= Wt:100.
Other REC Limits:N/K 
OSHA PEL:N/K 
OSHA STEL:N/K 
ACGIH TLV:N/K 
ACGIH STEL:N/K 

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:SEE TOXICOLOGICAL INFORMATION.
Routes of Entry: Inhalation:YES  Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:ACUTE: MAY BE HARMFUL BY INGESTION,
    INHALATION OR ABSORPTION THROUGH SKIN. MATERIAL MAY CAUSE
    IRRITATION TO THE EYES, SKIN, MUCOUS MEMBRANES, AND UPPER
    RESPIRATORY TRACT. CHRONIC: THERE IS LIMITED EVI DENCE THAT
    ETHIDIUM BROMIDE IS MUTAGENIC IN LABORATORY CELL CULTURES. UNTIL
    FURTHER TESTING HAS BEEN DONE, IT SHOULD BE TREATED AS A POSSIBLE
    MUTAGEN IN HUMANS.
Effects of Overexposure:SEE HEALTH HAZARDS.

=======================  First Aid Measures  =======================

First Aid:SKIN: WASH IMMEDIATELY WITH SOAP AND COPIOUS AMOUNTS OF WATER
    FOR AT LEAST 15 MINUTES. REMOVE CONTAMINATED CLOTHING AND SHOES AND
    WASH BEFORE WEARING. CONSULT A PHYSICIAN. EYES: FLUSH IMMEDIATELY
    WITH  COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. ASSURE
    ADEQUATE FLUSHING BY SEPARATING THE EYELIDS WITH FINGERS. CONSULT A
    PHYSICIAN. INHALATION: REMOVE TO FRESH AIR AND MONITOR BREATHING.
    IF BREAT HING BECOMES DIFFICULT, GIVE OXYGEN AND CONSULT A
    PHYSICIAN. IF BREATHING STOPS, GIVE ARTIFICIAL RESPIRATION AND
    CONSULT A PHYSICIAN. INGESTION: WASH MOUTH OUT WITH WATER AND
    CONSULT THE LOCAL POISON  CENTER AND A PHYSICIAN.

=====================  Fire Fighting Measures  =====================

Extinguishing Media:DRY CHEMICAL POWDER, CARBON DIOXIDE, WATER SPRAY,
    ALCOHOL OR POLYMER FOAM.
Fire Fighting Procedures:WEAR NIOSH APPROVED SCBA AND FULL PROTECTIVE
    EQUIPMENT .
Unusual Fire/Explosion Hazard:UPON THERMAL DECOMPOSITION, IT MAY EMIT
    TOXIC GASES.

==================  Accidental Release Measures  ==================

Spill Release Procedures:EVACUATE AREA. WEAR A NIOSH APPROVED
    RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS, AND HEAVY RUBBER
    GLOVES. SWEEP UP AND PLACE IN A SUITABLE CONTAINER. AVOID RAISING
    DUST. HOLD FOR APPROPRIATE DI SPOSAL. WASH SPILL SITE AND VENTILATE
    AREA AFTER MATERIAL PICKUP IS COMPLETE.

======================	Handling and Storage  ======================

Handling and Storage Precautions:STORE IN A TIGHTLY CLOSED CONTAINER IN
    A COOL, DRY PLACE (+20C). PROTECT FROM LIGHT. MATERIAL IS AN
    IRRITANT. POSSIBLE MUTAGEN.  AVOID CONTACT W/MATERIAL. AVOID
    PROLONGED/REPEATED EXPOSURE. LAB SHOULD  BE EQUIPPED WITH A SAFETY
    SHOWER & AN EYE WASH STATION. WASH THOROUGHLY AFTER HANDLING
    MATERIAL.
Other Precautions:MATERIAL SHOULD ONLY BE HANDLED BY QUALIFIED,
    EXPERIENCED PROFESSIONALS.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:USE A NIOSH APPROVED RESPIRATOR.
Ventilation:HANDLE IN A CHEMICAL FUME HOOD WITH ADEQUATE VENTILATION.
Protective Gloves:CHEMICAL RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EMERGENCY EYEWASH AND DELUGE
    SHOWER .
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
SYNONYMS: ETHIDIUM BROMIDE; HOMODIUM BROMIDE. MOLECULAR WEIGHT: 394.3.
    MOLECULAR FORMULA: C*21H*20N*3. BR.

==================  Physical/Chemical Properties  ==================

Melt/Freeze Pt:>260.C, 500.F
M.P/F.P Text:260C - 262C
Solubility in Water:SOLUBLE
Appearance and Odor:PURPLE-RED SOLID.

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
AVOID CONTACT WITH STRONG OXIDIZING AGENTS.
Stability Condition to Avoid:STABLE UNDER NORMAL HANDLING PROCEDURES.
Hazardous Decomposition Products:UPON THERMAL DECOMPOSITION, MAY EMIT
    TOXIC GASES INCLUDING CARBON MONOXIDE, CARBON DIOXIDE, NITROGEN
    OXIDES, AND HYDROGEN BROMIDE GAS.

===================  Toxicological Information	===================

Toxicological Information:RTECS #: SF7950000. TOXICITY DATA &
    REFERENCES: IPR; MUS; LDLO: 20 MG/KG ACTIVE AS ANTI-CANCER AGENT
    1974. CANCER RESEARCH. 34, 2699. SCU; MUS; LD50: 110 MG/KG 1952.
    ANNALS OF TROPICAL MEDICINE & PARA SITOLOGY. 46, 285. GENETIC DATA
    & REFERENCES: LEU; HMN; DOSE: 5 MG/L DNA DMG 1976. NATURE. 263,
    679. LVR; RAT; DOSE: 2500 NMOL/L UNSCHEDULED DNA SYNTHESIS 1989.
    CARCINOGENESIS (LONDON). 10, 393. HLA;  HMN; DOSE: 40 UMOL/L DNA
    INHIBITION 1982. MUTATION RESEARCH. 92, 427. FBR; HMN; DOSE: 2
    UMOL/L DNA ADDUCT 1975. CHEMICO-BIOLOGICAL INTERACTIONS. 11, 101.
    LNG; HAM; DOSE: 75 UMOL/L MUTATIONS IN MAMMALI AN SOMATIC CELLS
    1994. (ECOL INFO)

=====================  Ecological Information  =====================

Ecological:NO INFORMATION AVAILABLE. --CARCINOGENESIS (LONDON). 15,
    2303. FBR; MUS; DOSE: 1 MG/L CYTOGENETIC ANALYSIS 1975. MUTATION
    RESEARCH. 33, 417. LVR; RAT; DOSE; 10 MG/L SISTER CHROMATID
    EXCHANGE 1986. CEL L BIOLOGY & TOXICOLOGY. 2, 379. LYM; MU; DOSE:
    100 UMOL/L OTHER MUTATION TEST SYS 1972. BIOCHEM PHARMACOLOGY. 21,
    1977. REFER TO REGISTRY OF TOX EFTS OF CHEM SUBSTANCES (RTECS) FOR
    DEFINITION OF ABBRE VIATIONS USED IN ABOVE TEXT & FOR ADDNL INFO.
    THIS RPT CONTAINS ONLY SELECTED INFO FROM RTECS.

====================  Disposal Considerations  ====================

Waste Disposal Methods:COUNTRY, FEDERAL, STATE, & LOCAL REGULATIONS ARE
    VARIED & CHANGE FREQUENTLY. FOR THIS REASON, MANUFACTURER
    RECOMMENDS THAT YOU CONTACT YOUR LOCAL DEPARTMENT OF HEALTH
    SERVICES FOR INFORMATION ON THE D ISPOSAL OF THIS PRODUCT/ARRANGE
    FOR DISPOSAL BY A LICENSED DISPOSAL COMPANY. DISPOSE OF IN
    ACCORDANC E WITH LOCAL, STATE, & FEDERAL REGULATIONS .

===================  MSDS Transport Information  ===================

Transport Information:UN NUMBER: N/A. PROPER SHIPPING NAME: N/A. IATA
    CLASS: N/A. IATA PACKING GROUP: N/A.

=====================  Regulatory Information  =====================

Federal Regulatory Information:XI. RISK PHRASES: R36/37/38: IRRITATING
    TO EYES, RESPIRATORY SYSTEM AND SKIN. R46: MAY CAUSE HERITABLE
    GENETIC DAMAGE. SAFETY PHRASES: S22: DO NOT BREATHE DUST. S24/25:
    AVOID CONTACT WITH SKIN AND EYE S. S26: IN CASE OF CONTACT WITH
    EYES, RINSE IMMEDIATELY WITH PLENTY OF WATER AND SEEK MEDICAL
    ADVICE. S36/37/39: WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND
    EYE/FACE PROTECTION. S45: IN CASE OF ACCI DENT OR IF YOU FEEL
    UNWELL, SEEK MEDICAL ADVICE IMMEDIATELY. S53: AVOID EXPOSURE -
    OBTAIN SPECIAL IN STRUCTIONS BEFORE USE.
State Regulatory Information:

=======================  Other Information  =======================

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